41Origin of Life

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ORIGIN OF LIFE
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Origin of universe
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Big-bang Theory
Proposed by: Abbe Lemaitre (1931)
Age: Approximately 10^10 years
Description:
Current universe: About 20 billion years old with huge clusters of galaxies
Galaxies: Contain stars and clouds of gas and dust
Event: Singular huge explosion unimaginable in physical terms
Aftermath:
Expansion: Universe expanded causing temperature to decrease
Element formation: Hydrogen and Helium formed later
Galaxy formation: Gases condensed under gravitation to form present-day galaxies
Solar system formation: Formed about 4.6 billion years back in the milky way galaxy
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Origin of earth
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Formation
About 4.6 billion years back in the milky way galaxy
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Early conditions
Atmosphere: Initially absent
Surface composition: Covered by Methane(CH4), Ammonia(NH3), Water(H2O) and Carbon dioxide(CO2) released from molten mass
UV radiation effects:
Water breakdown: UV rays split water into Hydrogen(H2) and Oxygen(O2)
Hydrogen: Lighter Hydrogen escaped
Oxygen reactions: Combined with Methane (CH4) and Ammonia (NH3) to form Water (H2O), CO2 and others
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Early events
Bombardment period: Subjected to heavy bombardment with large comets and meteorites
Ocean vaporization: Heat from impacts periodically vaporized oceans
Life appearance: Appeared 0.5 billion years after Earth's formation (~4 billion years ago)
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Introduction
Timeline: Life appeared 0.5 billion years after Earth's formation (~4 billion years ago)
Significance: Considered a unique event in the history of universe
Early Earth: Could not support life when first formed
Life organization: Organized from non-living materials between Earth's formation and first fossils
Nature of life: Chemical phenomenon with chemical origin
Research: Since 1950, full-time research on origin of life studies in several laboratories worldwide
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Theories on origin of life
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Special creation theory
Support: Most of the world's major religions and civilizations
Religious texts:
Bible and Hindu philosophy: God created all living organisms
Key proponents:
Father Suarez: Spanish priest, greatest supporter of special creation theory
Archbishop Ussher: Claimed God created the world in October 4,004 BC (specific timeline provided)
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Abiogenesis/Spontaneous generation
Historical belief: Ancient Chinese, Babylonians and Egyptians believed life could arise spontaneously from non-living material
Examples:
Frogs: From damp Earth
Mice: From putrefied matter
Insects: From dew
Maggots: From decaying meat
Van Helmont's experiment: Claimed young mice could arise from wheat grains in a dark cupboard with a moist dirty shirt (1557-1644)
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Biogenesis (Life from life)
Opponents of spontaneous generation:
  1. Francesco Redi (1668)
  2. Abbe Lazzaro Spallanzani (1767)
  3. Louis Pasteur (1867)
Key experiments:
Redi experiment: Disproved spontaneous generation of flies from rotting meat
Spallanzani experiment:
Method: Sterilized nutritive broth by boiling meat in sealed flasks
Conclusion: Air carried microorganisms
Pasteur's swan-neck experiment:
Method: Used flasks that allowed air but not microorganisms
Conclusions:
  1. Demonstrated biogenesis
  2. Finally disproved spontaneous generation (1861)
  3. Didn't explain first life form
  4. Discovered role of bacteria in fermentation and anaerobic bacteria
Contributions:
  1. Germ theory of disease
  2. Principle of sterilization (Pasteurization)
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Cosmozoic theory/Spore theory
Proponents:
  1. Richter (1865)
  2. Arrhenius (1908)
Concept: Life transferred between planets as spores
Modern support: Some astronomers believe primitive life came via meteorites (Panspermia)
Evidence cited:
  1. UFO sightings
  2. Cave drawings of rocket-like objects
  3. 1996 NASA discovery of possible bacterial remains in Martian rock
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Catastrophism theory
Proposed by: Georges Cuvier (1796)
Concept: Simultaneous extinction and creation of life from inorganic material via natural cataclysms
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Oparin-Haldane theory
Proponents:
  1. Alexander Oparin (1924, expanded 1936)
  2. J.B.S. Haldane (1929)
Key concepts:
Primitive atmosphere: Reducing atmosphere without free oxygen
Modern atmosphere:
Composition:
  1. 78% molecular nitrogen
  2. 21% free oxygen (from photosynthesis)
  3. 1% argon
  4. 0.03% carbon dioxide
Nature: Strongly oxidizing
Essential condition: Presence of water
Energy sources:
  1. Solar radiation
  2. Lightning
  3. Volcanic ash
Chemical evolution:
First compounds: Methane, Ethylene, Acetylene (hydrocarbons)
Primordial soup: Organic compounds accumulated in oceans (Haldane's 'hot dilute soup')
Polymerization: Formed proteins, carbohydrates and fats
Experimental support:
Miller-Urey experiment (1953):
Apparatus: Spark discharge apparatus
Gases used: Methane(CH4), Ammonia(NH3), Hydrogen(H2) (2:1:2) and Water(H2O)
Results:
  1. Synthesized 15 amino acids including Glycine, Alanine, Valine, Proline, Aspartic acid
  2. Demonstrated formation of organic monomers
Melvin-Calvin experiment (1951):
Method: Irradiated CO2 and H2O in cyclotron
Products:
  1. Formic acid
  2. Succinic acid
  3. Oxalic acids
Recognition: Nobel Prize (1961)
Macromolecule evolution:
Polymer formation: Through dehydration synthesis
Hypotheses:
RNA-first hypothesis:
Concept: RNA could perform both genetic and enzymatic functions
Evidence:
  1. Ribozymes (catalytic RNA discovered by Thomas Cech and Sidney Altman, Nobel 1989)
  2. Some viruses have RNA genes
Implication: Early 'RNA world'
Protein-first hypothesis:
Proponent: Sidney Fox
Findings:
  1. Amino acids polymerize abiotically to form proteinoids
  2. Proteinoids form microspheres with cellular characteristics
Cairns-Smith's hypothesis:
Concept: Clay facilitated simultaneous polymerization of proteins and nucleic acids
Mechanism: Clay attracts organic molecules and contains catalytic metals (iron, zinc)
Protocell evolution:
Definition: Structure with lipid-protein membrane capable of energy metabolism
Formation theories:
Fox's microspheres: Lipids associate with proteinoids forming membranes
Oparin's coacervates: Concentrated macromolecules forming complex units that absorbed organic substances
Characteristics: Anaerobic chemoheterotrophs
First cells:
Features:
  1. Membrane boundary
  2. Heterotrophic fermenters with enzyme activity
  3. Capable of reproduction
Oldest fossils: 3.5 billion years old, resembling heterotrophic bacteria
Prokaryote evolution:
Timeline: Evolved before eukaryotes
Early types:
  1. Chemoheterotrophs (fermentation)
  2. Anaerobic chemoautotrophs
  3. Photosynthetic bacteria (initially only photosystem I)
Key developments:
  1. Cyanobacteria developed oxygenic photosynthesis (two photosystems)
  2. Archaeospheroides barbertonesis (oldest fossil, 3.2 billion years)
  3. Oxygen as first major pollutant
Genetic mechanisms:
  1. Binary fission (limited variability)
  2. Mutations as primary source of variation
Eukaryotic cell origin:
Oldest fossils: 1.5 billion years old
Energy metabolism: Aerobic cellular respiration
Classification history: Haeckel (1868) proposed kingdoms Monera (prokaryotes) and Protista (unicellular eukaryotes)
Evolutionary significance: Led to protists, fungi, plants and animals
Extraterrestrial life:
Potential location: Mars (no conclusive evidence found)
Q1.
Heredity and variation was postulated by
📅MOE 2008
Q2.
Charles Darwin's theory of evolution is based on
📅MOE 2064
Q3.
Most accepted theory for origin of life is
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Q4.
Organs which have same basic structure and origin but differ in function are called
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Q5.
Wings of birds and insects are
📅MOE 2061
Q6.
Fins of fishes and flipper of whale are
📅MOE 2003
Q7.
Inheritance of acquired character is given by the concept of
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Q8.
Theory of continuity of germ plasm was proposed by
📅MOE 2033
Q9.
Postulation of the theory of natural selection published in 1858 was given by
📅MOE 2054
Q10.
Organs having similar function but different structure or origin are called
📅IOM 2007
Q11.
The mutation theory of evolution was proposed by
📅IOM 2004
Q12.
Which of the following is a living fossil?
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Q13.
Which of the following is a connecting link between animal and plant kingdom?
📅IOM 2003
Q14.
Founder of palaeontology is
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Q15.
The main drawback of Darwin's theory is
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Q16.
Earlier organisms were
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Q17.
Three stages of evolution was given by
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Q18.
The sun, earth and stars are reformed from
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Q19.
Correct sequence among the following is
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Q20.
Coacervates are clusters of
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Q21.
The organisms which depended on organic molecules present in primitive ocean were referred as
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Q22.
The study of fossils is called
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Q23.
Wings of mosquito, bat and sparrow exhibit the phenomenon called
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Q24.
Phylogeny represents
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Q25.
Which is not a universal character of protoplasm?
📅MOE 2003
Q26.
Protoplasm is
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Q27.
Peripatus is a connecting link between
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Q28.
According to neo-Darwinism, evolution is due to
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Q29.
Two sets of muscles responsible for ear movement are
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Q30.
During vertebrate brain evolution, the part showing greatest evolution by acquiring large size is
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Q31.
The morphological study based on phylogenetic characters and homologous development is
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Q32.
The study of evidence of origin of evolution and its branches according to phylogenetic tree is called
📅IE 2002
Q33.
Fossils are mostly found in
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Q34.
Natural selection acts directly on
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Q35.
Evolution of photosynthetic ability resulted in division of living world into
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Q36.
Allopatric speciation is caused by
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Connecting link between arthropoda and annelida is
📅BPKIHS 2014
Q38.
Who gave the principle of biogenetic law?
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Q39.
During evolution of earth, the first compound formed was
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Q40.
Which gas was most abundant during earth formation?
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Q41.
Sudden appearance of tail in a small baby is an example of
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Q42.
Connecting link between animal and plant is
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Q43.
Which of the following is closest to man?
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Q44.
The main strong evidence for evolution is
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Q45.
The most basic substance of origin of life is
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Q46.
Harold C. Urey's laboratory experiment found large number of complex organic compounds, among which the essentials of life were
📅MOE 2014MOE 2013
Q47.
Stout-running forelegs of horse and forearms of human used for catching are
📅MOE 2014
Q48.
Canine teeth in man are
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Q49.
Gill slits present in embryonic stage of vertebrates represent
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Q50.
The word coacervate was first used by
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Q51.
Modern human beings were originated from
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Q52.
Origin of species was postulated by
📅MOE 2062
Q53.
Which of the following were first formed?
📅KU 2015
Q54.
The concept of survival of the fittest was advanced by
📅KU 2015
Q55.
The term Homo sapiens was coined by
📅KU 2015
Q56.
Recapitulation theory means that
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Q57.
Darwin's statement 'survival of the fittest' means that
📅KU 2012
Q58.
The process of inheritance of character in living beings is called
📅KU 2011
Q59.
The principle of inheritance of acquired characters was given by
📅KU 2011