3Cell cycle

📚
REASON FOR CELL CYCLE / CELL DIVISION
Core Reason:
  • Cell divides to maintain balance between bulk of cytoplasm and nucleus
  • Cell division restores high surface area : volume ratio
  • Cell division restores high nucleocytoplasmic ratio
Nucleocytoplasmic Ratio:
Formula: Nucleocytoplasmic ratio = Vₙ / Vcyto = Vₙ / (Vcell − Vₙ)
Synonym: Karyoplasmic ratio
Important Points:
  • In a cell going to divide, nucleocytoplasmic ratio decreases
  • Surface area per unit volume also decreases
  • Increase in nucleocytoplasmic ratio indicates increasing cell division activity
  • Smaller cells are metabolically more active due to high nucleocytoplasmic ratio
📚
CHROMOSOME AND DNA AMOUNT
Basic Rule:
  • Every chromosome has 2 chromatids after DNA replication
  • Exception: daughter chromosome has 1 chromatid
  • Chromosome number and DNA amount change differently during cell cycle

Table 1: Chromosome / DNA Recall

Stage
Chromosome Number
DNA Amount
Chromatid Status
G1
2n
2C
1 chromatid / chromosome
S phase
2n
2C → 4C
DNA replication
G2
2n
4C
2 chromatids / chromosome
Metaphase of mitosis
2n
4C
2 chromatids / chromosome
Anaphase of mitosis
4n temporarily
4C
Sister chromatids separate as daughter chromosomes
After mitosis
2n in each daughter cell
2C each
1 chromatid / chromosome
Metaphase-I
2n
4C
2 chromatids / chromosome
Anaphase-I
n at each pole
2C at each pole
Centromere not divided; chromatids remain paired
After meiosis-II
n
1C
1 chromatid / chromosome
📚
CELL CYCLE
Definition:
  • Cell cycle = sequence of events between two cell divisions
  • Cell accumulates nutrition and then divides into daughter cells
  • Cell division = process of forming daughter cells from parent cell
Generation Time: Total time taken by parent cell to divide into daughter cells
Main Events:
  1. DNA replication
  2. Nuclear division / karyokinesis
  3. Cytoplasmic division / cytokinesis
Phases:
  • Interphase / I-phase
  • Mitotic phase / M-phase
Sequence:
  • G1 → S → G2 → M
  • S → G2 → M → G1
  • G2 → M → G1 → S
  • M → G1 → S → G2
Duration Points:
  • G1 = most variable phase of cell cycle
  • G2 = shortest phase of interphase
  • M-phase = shortest phase of whole cell cycle
📚
INTERPHASE
Synonyms:
  • I-phase
  • Non-dividing phase
  • Resting phase
  • Metabolic phase
  • Growth phase
  • Preparative phase
  • Invisible phase
Important Points:
  • Longest phase of cell cycle
  • Called resting phase because nucleus is not dividing
  • Actually metabolically / physiologically most active phase
  • Nucleus is largest during interphase
  • Replicated chromosomes are not visible
  • Transcription occurs throughout interphase
  • Transcription rate highest in G1 phase
Subphases:
  • G1 phase
  • S phase
  • G2 phase
📚
G1 PHASE
Synonyms:
  • Gap I
  • Growth I
  • Post-mitotic phase
  • Pre-DNA synthesis phase
Main Nature:
  • Preparatory phase of DNA synthesis
  • Maximum growth occurs in G1 phase
  • Decision of cell division occurs in this phase
Synthesis:
  • RNA: tRNA, mRNA, rRNA
  • Ribosomes
  • Histone protein synthesis starts
  • Bulk histone synthesis occurs in S phase
  • Non-histone proteins
  • Structural proteins
  • Functional proteins
  • Enzymes: DNA polymerase, RNA polymerase
Absent In:
  • Amoeba
  • Slime moulds
  • Yeast
Restriction Point:
  • Also called R-point / checkpoint
  • Present in G1 phase
  • After crossing this point or entering S phase, division becomes compulsory
Non-dividing Cell: Non-dividing cells remain in G1 / enter G0
📚
G0 PHASE
Synonyms:
  • Quiescent stage
  • Quiet stage
Definition: Stage of arrest of cell cycle and onset of differentiation
Examples:
  • Cells of quiescent centre in root tip
  • Skeletal muscle cells
  • Nerve cells
  • RBC
📚
S PHASE
Synonyms:
  • Synthetic phase
  • DNA synthesis phase
Nature:
  • Metabolically most active stage
  • Invisible phase of mitosis because replicated chromosomes are not visible
  • After S phase, cell can enter division without interruption
Synthesis:
  • Replication / synthesis of nuclear DNA
  • DNA replication occurs with DNA polymerase
  • DNA polymerase is active
  • Histone protein synthesis
Chromosome Status: Each chromosome has 2 chromatids after S phase
📚
G2 PHASE
Synonyms:
  • Gap II
  • Growth II
  • Pre-mitotic phase
  • Post-DNA synthesis phase
  • Resting phase of interphase
Events:
  • Replication of cytoplasmic DNA
  • Synthesis of organelles required for M phase
  • Synthesis of tubulin protein for spindle apparatus
  • Energy storage
  • Centriole duplication
  • Cell contains double DNA amount compared to original diploid cell
Special Points:
  • Division of chloroplast and mitochondria starts in G2
  • Division of chloroplast and mitochondria continues up to cytokinesis
  • In meiotic cell division, G2 phase is very short or almost absent
📚
MITOTIC PHASE
Synonyms:
  • M-phase
  • Dividing phase
  • Cell division
Important Points:
  • Shortest phase of cell cycle
  • Includes karyokinesis and cytokinesis
Components:

Table 1: Components of M Phase

Component
Meaning
Karyokinesis
Nuclear division
Cytokinesis
Division of cytoplasm
Cell plate
Plant cytokinesis
Constriction / furrowing
Animal cytokinesis
Types of Cell Division:
  • Amitosis
  • Mitosis
  • Meiosis
📚
AMITOSIS
Synonyms:
  • Direct cell division
  • Incipient cell division
  • Primitive cell division
Features:
  • Division completes without spindle fibre formation
  • Unequal cell division
  • Main method of division in prokaryotic cells
  • Also occurs in some eukaryotic cells like Saccharomyces / yeast
  • Nuclear membrane persists throughout nuclear division
Examples:
  • Budding
  • Fission
📚
MITOSIS
Synonyms:
  • Somatic cell division
  • Indirect cell division
  • Homotype cell division
  • Equational cell division
Special Note: On the basis of DNA, mitosis may be considered reductional in the given note
Best Material: L.S. of onion root tip
Occurrence:
  • Unicellular eukaryotes
  • Multicellular eukaryotes
  • Haploid, diploid and polyploid cells
  • Somatic cells
  • Reproductive cells
Result: Single cell → 2 daughter cells
Mitocyte: Cell undergoing mitosis
Calculations:

Table 1: Mitosis Formulae

Question Type
Formula
Total mitotic divisions/events needed to produce n cells from one cell
n − 1
Number of cells after n generations
2ⁿ
Number of generations to form given cells
2ⁿ = given number
Types Based on Spindle Formation:

Table 1: Types of Mitosis

Type
Feature
Common In
Astral / amphiastral mitosis
Mitosis with spindle fibre formation
Animals
Anastral mitosis
Mitosis without astral spindle formation
Plants
📚
MITOTIC KARYOKINESIS
Stages:
  • Prophase
  • Metaphase
  • Anaphase
  • Telophase
Important Point: All 4 stages occur continuously without stoppage
📚
PROPHASE OF MITOSIS
Key Features:
  • First stage of mitosis
  • Longest stage of mitosis
  • Metabolically most active stage of cell division
  • Chromatin changes into chromosomes
  • Chromosomes become visible
  • Prophase chromosomes = prochromosomes
  • Spiralisation occurs
  • Spiralisation type = plectonemic coiling
  • Cell becomes more viscous
  • Spindle fibre formation starts during late prophase
  • Nuclear membrane disappears during late prophase
  • Nucleoplasm disappears during late prophase
  • Nucleolus disappears during late prophase
Not Visible:
  • Centromere not visible
  • Chromatids not visible
Spindle Fibre:
  • Made of 97% tubulin protein
  • Made of 3% RNA
CEE Trap:
  • Plectonemic coiling → mitotic prophase
  • Paranemic coiling → meiotic prophase
📚
METAPHASE OF MITOSIS
Key Features:
  • Chromosomes are thickest
  • Chromosomes are shortest
  • Centromere visible
  • Chromatids visible
  • Best stage to study chromosomes
  • Metaphase-II is better than metaphase-I for chromosome study
  • Chromosomes arrange in single line at equator
  • Arrangement at equator = metakinesis
  • Single metaphasic / equatorial plate formed
  • Structure, size and number of chromosomes studied
  • Spindle fibre well developed
  • Spindle fibres from opposite poles attach to kinetochore / primary constriction
  • Idiogram / karyotype prepared
Chromatid Count: Number of chromatids per chromosome = 2 in mitosis and meiosis metaphase
📚
ANAPHASE OF MITOSIS
Synonym: Migratory phase
Key Features:
  • Shortest stage of mitosis
  • Inert / less active stage of cell division
  • Best stage to study chromosome shape
  • Centromere divides
  • Sister chromatids separate
  • Sister chromatids move towards opposite poles
  • Each chromosome has 1 chromatid in anaphase
  • Poleward movement occurs due to spindle fibre and centromere
  • Main force for poleward movement generated by centromere
  • Calcium ions promote anaphase
Chromosome Shapes:
  • V-shaped
  • J-shaped
  • L-shaped
  • I-shaped
Special Note: Chromosome number remains same but chromatid number becomes half compared to metaphase
📚
TELOPHASE OF MITOSIS
Synonym: Re-organisation phase
Key Features:
  • Reverse of prophase
  • Nuclear membrane reappears
  • Nucleolus reappears
  • Chromosomes decondense
  • Chromosomes uncoil
  • Chromosomes reach opposite poles
  • Spindle fibres disappear
  • Chromosomes reorganise
  • Cell resumes metabolic activity
Result: Two daughter nuclei with same chromosome number and same DNA amount
📚
CYTOKINESIS

Table 1: Plant vs Animal Cytokinesis

Feature
Plant Cell
Animal Cell
Method
Cell plate formation
Furrowing / constriction
Initiating structure
Golgi body initiates cell plate
Microfilaments form contractile ring
Plane determined by
Microtubules
Microfilaments
Growth direction
Centrifugal
Centripetal
Final result
Phragmoplast → cell plate → cell wall
Cleavage furrow divides cytoplasm
Plant Cell Plate Formation:
  • Spindle fibres aggregate at equator
  • Golgi body initiates cell plate formation
  • Cell plate later converts into phragmoplast and finally cell wall
📚
SPECIAL POINTS OF MITOSIS
Daughter Cells:
  • Same amount of DNA as parent cell
  • Same number of chromosomes as parent cell
  • Genetically identical cells
C-Mitosis:
  • Colchicine-treated mitosis
  • Colchicine = mitotic poison
  • Temporarily stops mitotic division
  • Inhibits spindle fibre formation
  • Breaks microtubules
  • Arrests cell division at metaphase
  • Produces polyploidy
Uncontrolled Mitosis: Leads to neoplasia
Example Calculations:

Table 1: CEE Calculation Examples

Question
Answer
Mitotic division events needed to form 64 cells
64 − 1 = 63 total division events
Generations needed to form 32 cells
2ⁿ = 32 → n = 5
Bacteria divides every 20 min; cells after 2 hr
2 hr = 120 min; 120/20 = 6 generations; 2⁶ = 64
Bacteria fills cup in 60 min, divides every 1 min; half cup time
59 min
Bacteria fills cup in 60 min, divides every 3 min; half cup time
57 min
📚
SIGNIFICANCE OF MITOSIS
Points:
  • Growth of organism
  • Maintenance of somatic cells
  • Repair of somatic cells
  • Maintains genetic stability
  • Avoids ageing by replacing old cells
  • Produces genetically identical cells resembling zygote
  • Restores surface area : volume ratio
  • Restores nucleocytoplasmic ratio by dividing mature cell into smaller cells
📚
MEIOSIS
Synonyms:
  • Reductional cell division
Introduction:
  • Common in germ cells / reproductive cells
  • Single cell divides to form 4 daughter cells
  • Occurs in pollen mother cell
  • Two divisions of nucleus
  • Only one division of chromosome
  • Meiotic cell = meiocyte
  • Meiocyte divides once in lifetime
  • Meiosis is never followed by meiosis
  • Meiosis can be followed by mitosis
  • In alternation of generation, meiosis is always followed by fusion / fertilization
  • Occurs in diploid and polyploid cells
  • Never occurs in haploid cells
Best Material:
  • Anthers of onion
  • Tradescantia
  • Anther / microsporangium / microspore mother cell
Result Compared to Diploid Parent:
  • Same amount of DNA according to given note
  • Half number of chromosomes
Gamete Production:

Table 1: Spermatocyte / Oocyte Output

Starting Cell
Output
1 primary spermatocyte / 2n
4 sperms
1 primary oocyte / 2n
1 egg
1 secondary spermatocyte / n
2 sperms
1 secondary oocyte / n
1 egg
Double Division:
  • Meiosis-I
  • Meiosis-II
📚
MEIOSIS-I
Nature: Reductional division
Components:
  • Karyokinesis
  • Cytokinesis
Stages:
  • Prophase-I
  • Metaphase-I
  • Anaphase-I
  • Telophase-I
📚
PROPHASE-I
Importance:
  • Longest phase of meiosis
  • Most complex phase of meiosis
  • Longest and most complex phase = Prophase-I
Substages:

Table 1: Prophase-I Substages

Stage
Main Character
Leptotene
Bouquet formation
Zygotene
Synapsis
Pachytene
Crossing over; chiasmata formation starts
Diplotene
Chiasmata visible / completed; terminalisation starts
Diakinesis
Terminalisation completes
📚
LEPTOTENE
Features:
  • Chromosomes are thread-like
  • Chromosomes show beads called chromomeres
  • Bouquet formation occurs
  • Called bouquet stage
  • Best stage for observation of chromomere
Trap:
  • Chromomere = bead structure in meiotic chromosome
  • Nucleosome = bead structure in chromatin
📚
ZYGOTENE
Main Event: Synapsis
Synapsis:
  • Lengthwise pairing of homologous chromosomes
  • Precise chromomere-to-chromomere pairing
  • Also called syndesis / zipping
  • Occurs in zipper-like fashion
  • May begin at centromere, ends or any point
Synaptonemal Complex:
  • Protein complex favouring synapsis
  • Tripartite structure
Bivalent:
  • Each paired homologous chromosome pair = bivalent
  • Exists as dyad / 2-stranded stage in zygotene
  • Bivalent produced in diploid and allopolyploid
  • Multivalent produced in autopolyploid
  • Number of bivalents = half total chromosomes in diploid cell
Other Features:
  • Chromosomes thicken
  • Chromosomes shorten
📚
PACHYTENE
Importance:
  • Longest substage of Prophase-I
  • Most important substage of Prophase-I
  • Chromosomes are thickest
  • Morphological details of chromosome best studied
Crossing Over:
  • Exchange of genetic material / chromatid segment / DNA / genes
  • Occurs at 4-stranded stage
  • Equal exchange between non-sister chromatids of homologous chromosomes
  • Major source of continuous variation in sexually reproducing organisms
  • Ultimate source of variation = mutation
  • Mutation produces discontinuous variation
Crossing Over Frequency: Single crossing over > double crossing over > triple crossing over
Enzymes:

Table 1: Enzymes of Crossing Over

Enzyme
Function
Endonuclease
Breakdown / nicking
Unwindase
Separation
Ligase
Rejoining
Tetrad Formation:
  • Sister chromatids become visible
  • Bivalent exists as tetrad
  • Tetrad contains 2 homologous chromosomes
  • Tetrad contains 4 chromatids
  • Tetrad contains 2 centromeres
  • Tetrad contains 4 kinetochores
Synapsis Status:
  • Synapsis mature
  • Synaptonemal complex mature
  • Bivalent mature
📚
DIPLOTENE
Features:
  • Chiasmata formation takes place / becomes clearly visible
  • Synaptonemal complex starts dissolving except at chiasmata
  • Chiasmata indicates crossing over
  • Terminalisation starts
Important Clarification:
  • Chiasmata formation starts during pachytene
  • Chiasmata clearly visible during diplotene
Lampbrush Chromosomes:
  • Profuse decondensation occurs
  • Seen in female species producing yolky eggs
  • Examples: all vertebrates and some invertebrates
Human Female: Ovum remains in diplotene stage from birth to puberty; diplotene is longest in human female
📚
DIAKINESIS
Features:
  • Chiasmata disappear due to terminalisation
  • Terminalisation completes
  • Chiasmata move from centromere to telomere in zipper-like fashion
  • At end, each chromosome has two chromatids = dyad
  • Spindle fibre formation starts
  • Nuclear membrane starts disappearing
  • Nucleolus starts disappearing
  • Nucleoplasm starts disappearing
Terminalisation Note:
  • Terminalisation starts before / by diakinesis as per note sequence
  • Terminalisation occurs and ends during diakinesis
📚
SYNAPTONEMAL COMPLEX
Features:
  • Feature of meiotic Prophase-I
  • Characteristic protein mentioned = ubiquitin
  • First observed by Moses
  • Appears in zygotene
  • Persists in pachytene
  • More clear in pachytene
  • Disappears during diplotene
  • Helps proper pairing of homologous chromosomes
  • Helps recombination
📚
METAPHASE-I
Features:
  • Paired homologous chromosomes arrange at equatorial plane
  • Arrangement = congression
  • Chromosomes arrange in two distinct lines
  • Double metaphase plate formed
  • Spindle fibres appear
  • Each chromosome has 2 chromatids and 1 centromere
📚
ANAPHASE-I
Features:
  • Separation of maternal and paternal homologous chromosomes
  • Separation = disjunction
  • Separated chromosomes = univalents / dyads
  • Centromere does not divide
  • Chromosome number reduces to half
  • Chromatid number remains same compared to metaphase-I
📚
TELOPHASE-I
Features:
  • Similar to mitotic telophase
  • Daughter nuclei form after first meiotic division
  • Followed by cytokinesis
📚
INTERKINESIS
Definition: Brief intrameiotic interphase between meiosis-I and meiosis-II
Important Point:
  • No S phase
  • No DNA synthesis
  • Occurs between meiosis-I and meiosis-II
📚
MEIOSIS-II
Synonym: Meiotic mitosis
Nature: Similar to mitosis
Stages:
  • Prophase-II
  • Metaphase-II
  • Anaphase-II
  • Telophase-II
Components:
  • Karyokinesis
  • Cytokinesis
Cytokinesis Types:

Table 1: Cytokinesis in Meiosis

Type
Wall Formation
Tetrad Formed
Successive type
Both meiosis-I and meiosis-II followed by wall formation
Isobilateral tetrads
Simultaneous type
Meiosis-I not followed by wall formation; wall formation after meiosis-II
Tetrahedral tetrads
📚
SIGNIFICANCE OF MEIOSIS
Points:
  • Maintains constant chromosome number in sexually reproducing organisms
  • Crossing over causes recombination
  • Recombination has role in evolution
  • Shows basic relationship among organisms
Numerical Points:
  • Number of cytokinesis in meiosis = 3
  • 1 cytokinesis in meiosis-I + 2 cytokinesis in meiosis-II
  • Number of spindles in meiosis = 3
  • 1 spindle in metaphase-I + 2 spindles in metaphase-II
  • Chromatids per chromosome = 2 in metaphase of mitosis / meiosis
  • Chromatids per chromosome = 1 in anaphase of mitosis
  • Chromatids per chromosome = 2 in anaphase-I of meiosis
📚
MITOSIS VS MEIOSIS

Table 1: High-Yield Comparison

Feature
Mitosis
Meiosis
Common site
Somatic cells
Germ / reproductive cells
Best material
L.S. onion root tip
Onion / Tradescantia anther
Number of divisions
One
Two
Daughter cells
2
4
Chromosome number
Maintained
Reduced to half
Genetic nature
Identical daughter cells
Variable daughter cells due to crossing over
Synapsis
Absent
Present in zygotene
Crossing over
Absent
Present in pachytene
Centromere division
Anaphase
Anaphase-II; not in anaphase-I
Function
Growth, repair, maintenance
Gamete formation, variation, chromosome number maintenance
Q1.
Chiasmata formation takes place in [MOE 2058]
📅MOE 2058
Q2.
Meiosis occurs in [MOE 2055]
📅MOE 2055
Q3.
Chromosomes are seen distinctly during [BPKIHS 1997]
📅BPKIHS 1997
Q4.
Mitosis can be clearly observed from: [BPKIHS 1997]
📅BPKIHS 1997
Q5.
The smallest unit of crossing over is [BPKIHS 1998]
📅BPKIHS 1998
Q6.
When only G, phase is operating and others are no operating the phase is [BPKIHS 1998]
📅BPKIHS 1998
Q7.
Synapsin occurs in which stage: [MOE - 2008]
📅MOE - 2008
Q8.
The no. of chromatids in a chromosomes at metaphase is: [MOE-2002]
📅MOE-2002
Q9.
In meiosis cell division, nuclear membrane disappear and chromosomes are separated during: [MOE-2053)
📅MOE-2053)
Q10.
The two daughter cells produced at the end of meiosis when compared to the parent diploid cells will have: [IOM-2004)
📅IOM-2004)
Q11.
Nucleus has maximum size during: [IOM- 20]
📅IOM- 20%
Q12.
Which of the following is associated with division? [IOM-200]
📅IOM-200
Q13.
How many times does a simple cell divide mitotical to form 32 cells? [IOM-20]
📅IOM-20
Q14.
In which stage does centromere divide? [IOM- 20]
📅IOM- 20 
Q15.
The inherent capacity of a cell to regenerate a total plant is called. [IOM- 195
📅IOM- 195
Q16.
Interphase, chromatin under electron microscope refers to: [BPKIHS 200]
📅BPKIHS 200
Q17.
The mitosis can be readily observed in: [BPKIHS 200)
📅BPKIHS 200)
Q18.
During meiosis, which is correct? [BPKIHS 2001
📅BPKIHS 2001
Q19.
During which phase chromatids are clearly seen: [BPKIHS 200]
📅BPKIHS 200%
Q20.
Homologous chromosome separate during: [BPKIHS 2002
📅BPKIHS 2002
Q21.
During meiosis gametes produced are: [BPKIHS 2002)
📅BPKIHS 2002)
Q22.
No. of chromosomes in sister cells immediately after mitotic metaphase are: [BPKIHS 2003)
📅BPKIHS 2003)
Q23.
Karyokinesis is the division of:
📅BPKIHS 2005
Q24.
Terminalisation takes place during:
📅BPKIHS 2005
Q25.
The site where meiosis occur in a plant is:
📅BPKIHS 2006
Q26.
A cell stops growing due to storage of nutrients, this would happen in:
📅BPKIHS 2007
Q27.
In cell division replication of DNA occurs in
📅IE - 2002
Q28.
During the start of mitosis the condensed chromosome contains 2
📅IE - 2002
Q29.
Which of the following is the part of mitosis in seed plants?
📅IE - 2002
Q30.
During cell cycle, two molecules of DNA are present in chromosome during
📅IE -2003
Q31.
The transfer of genes from one chromosome to another during synapsis, is termed as:
📅IE - 2004
Q32.
Crossing over occurs during
📅IE - 2005
Q33.
Replication of DNA occurs during
📅IE - 2005
Q34.
The region of attachment of chromosome to spindle fibre is called
📅IE - 2005
Q35.
Segregation of dominant and recessive genes occur during:
📅IE - 2008
Q36.
The point at which crossing over takes place is [BPKIHS - 2016, 2012]
📅BPKIHS - 2016, 2012
Q37.
The phase of cell cycle in which nucleolus and nuclear membrane disappear is [BPKIHS - 2016)
📅BPKIHS - 2016)
Q38.
What is the correct order of prophase I of meiosis I? [BPKIHS - 2013]
📅BPKIHS - 2013
Q39.
Chromosomes becomes distinct and nucleolus as well as nuclear membrane disappears is [BPKIHS - 2012]
📅BPKIHS - 2012
Q40.
Centrosome helps in [BPKIHS - 2011]
📅BPKIHS - 2011
Q41.
Shortest phase of cell cycle is: [BPKIHS - 2010]
📅BPKIHS - 2010
Q42.
Correct sequence of cell cycle is
📅IOM-2014
Q43.
The main significance of M-phase of the cell cycle is
📅IOM-2013
Q44.
Terminalization occurs in
📅IOM-2016
Q45.
The mitotic poison is
📅IOM-2012
Q46.
In which stage chromosome are arranged in equator?
📅IOM-2012
Q47.
In meiosis, bivalent is attached to spindle fiber at
📅IOM-2012
Q48.
The amount of DNA doubles in which mitotic phase
📅MOE 2014
Q49.
At what stage of mitotic division, formation daughter nuclei takes place?[MOE 2016
📅MOE 2016
Q50.
The pairing (synapsid) of chromosome occurs in the following stage of meiosis-I [MOE 2068)
📅MOE 2068)
Q51.
In which stage of the meiotic cell division crossing over occurs? [MOE 2010)
📅MOE 2010)
Q52.
Centromere completely divides into two separate chromatids at [MOE 2010)
📅MOE 2010)