📚
REASON FOR CELL CYCLE / CELL DIVISION
▢ Core Reason:
- •Cell divides to maintain balance between bulk of cytoplasm and nucleus
- •Cell division restores high surface area : volume ratio
- •Cell division restores high nucleocytoplasmic ratio
▢ Nucleocytoplasmic Ratio:
❖ Formula: Nucleocytoplasmic ratio = Vₙ / Vcyto = Vₙ / (Vcell − Vₙ)
❖ Synonym: Karyoplasmic ratio
❖ Important Points:
- •In a cell going to divide, nucleocytoplasmic ratio decreases
- •Surface area per unit volume also decreases
- •Increase in nucleocytoplasmic ratio indicates increasing cell division activity
- •Smaller cells are metabolically more active due to high nucleocytoplasmic ratio
📚
CHROMOSOME AND DNA AMOUNT
▢ Basic Rule:
- •Every chromosome has 2 chromatids after DNA replication
- •Exception: daughter chromosome has 1 chromatid
- •Chromosome number and DNA amount change differently during cell cycle
Table 1: Chromosome / DNA Recall
Stage | Chromosome Number | DNA Amount | Chromatid Status |
|---|---|---|---|
G1 | 2n | 2C | 1 chromatid / chromosome |
S phase | 2n | 2C → 4C | DNA replication |
G2 | 2n | 4C | 2 chromatids / chromosome |
Metaphase of mitosis | 2n | 4C | 2 chromatids / chromosome |
Anaphase of mitosis | 4n temporarily | 4C | Sister chromatids separate as daughter chromosomes |
After mitosis | 2n in each daughter cell | 2C each | 1 chromatid / chromosome |
Metaphase-I | 2n | 4C | 2 chromatids / chromosome |
Anaphase-I | n at each pole | 2C at each pole | Centromere not divided; chromatids remain paired |
After meiosis-II | n | 1C | 1 chromatid / chromosome |
📚
CELL CYCLE
▢ Definition:
- •Cell cycle = sequence of events between two cell divisions
- •Cell accumulates nutrition and then divides into daughter cells
- •Cell division = process of forming daughter cells from parent cell
▢ Generation Time: Total time taken by parent cell to divide into daughter cells
▢ Main Events:
- DNA replication
- Nuclear division / karyokinesis
- Cytoplasmic division / cytokinesis
▢ Phases:
- •Interphase / I-phase
- •Mitotic phase / M-phase
▢ Sequence:
- •G1 → S → G2 → M
- •S → G2 → M → G1
- •G2 → M → G1 → S
- •M → G1 → S → G2
▢ Duration Points:
- •G1 = most variable phase of cell cycle
- •G2 = shortest phase of interphase
- •M-phase = shortest phase of whole cell cycle
📚
INTERPHASE
▢ Synonyms:
- •I-phase
- •Non-dividing phase
- •Resting phase
- •Metabolic phase
- •Growth phase
- •Preparative phase
- •Invisible phase
▢ Important Points:
- •Longest phase of cell cycle
- •Called resting phase because nucleus is not dividing
- •Actually metabolically / physiologically most active phase
- •Nucleus is largest during interphase
- •Replicated chromosomes are not visible
- •Transcription occurs throughout interphase
- •Transcription rate highest in G1 phase
▢ Subphases:
- •G1 phase
- •S phase
- •G2 phase
📚
G1 PHASE
▢ Synonyms:
- •Gap I
- •Growth I
- •Post-mitotic phase
- •Pre-DNA synthesis phase
▢ Main Nature:
- •Preparatory phase of DNA synthesis
- •Maximum growth occurs in G1 phase
- •Decision of cell division occurs in this phase
▢ Synthesis:
- •RNA: tRNA, mRNA, rRNA
- •Ribosomes
- •Histone protein synthesis starts
- •Bulk histone synthesis occurs in S phase
- •Non-histone proteins
- •Structural proteins
- •Functional proteins
- •Enzymes: DNA polymerase, RNA polymerase
▢ Absent In:
- •Amoeba
- •Slime moulds
- •Yeast
▢ Restriction Point:
- •Also called R-point / checkpoint
- •Present in G1 phase
- •After crossing this point or entering S phase, division becomes compulsory
▢ Non-dividing Cell: Non-dividing cells remain in G1 / enter G0
📚
G0 PHASE
▢ Synonyms:
- •Quiescent stage
- •Quiet stage
▢ Definition: Stage of arrest of cell cycle and onset of differentiation
▢ Examples:
- •Cells of quiescent centre in root tip
- •Skeletal muscle cells
- •Nerve cells
- •RBC
📚
S PHASE
▢ Synonyms:
- •Synthetic phase
- •DNA synthesis phase
▢ Nature:
- •Metabolically most active stage
- •Invisible phase of mitosis because replicated chromosomes are not visible
- •After S phase, cell can enter division without interruption
▢ Synthesis:
- •Replication / synthesis of nuclear DNA
- •DNA replication occurs with DNA polymerase
- •DNA polymerase is active
- •Histone protein synthesis
▢ Chromosome Status: Each chromosome has 2 chromatids after S phase
📚
G2 PHASE
▢ Synonyms:
- •Gap II
- •Growth II
- •Pre-mitotic phase
- •Post-DNA synthesis phase
- •Resting phase of interphase
▢ Events:
- •Replication of cytoplasmic DNA
- •Synthesis of organelles required for M phase
- •Synthesis of tubulin protein for spindle apparatus
- •Energy storage
- •Centriole duplication
- •Cell contains double DNA amount compared to original diploid cell
▢ Special Points:
- •Division of chloroplast and mitochondria starts in G2
- •Division of chloroplast and mitochondria continues up to cytokinesis
- •In meiotic cell division, G2 phase is very short or almost absent
📚
MITOTIC PHASE
▢ Synonyms:
- •M-phase
- •Dividing phase
- •Cell division
▢ Important Points:
- •Shortest phase of cell cycle
- •Includes karyokinesis and cytokinesis
▢ Components:
Table 1: Components of M Phase
Component | Meaning |
|---|---|
Karyokinesis | Nuclear division |
Cytokinesis | Division of cytoplasm |
Cell plate | Plant cytokinesis |
Constriction / furrowing | Animal cytokinesis |
▢ Types of Cell Division:
- •Amitosis
- •Mitosis
- •Meiosis
📚
AMITOSIS
▢ Synonyms:
- •Direct cell division
- •Incipient cell division
- •Primitive cell division
▢ Features:
- •Division completes without spindle fibre formation
- •Unequal cell division
- •Main method of division in prokaryotic cells
- •Also occurs in some eukaryotic cells like Saccharomyces / yeast
- •Nuclear membrane persists throughout nuclear division
▢ Examples:
- •Budding
- •Fission
📚
MITOSIS
▢ Synonyms:
- •Somatic cell division
- •Indirect cell division
- •Homotype cell division
- •Equational cell division
▢ Special Note: On the basis of DNA, mitosis may be considered reductional in the given note
▢ Best Material: L.S. of onion root tip
▢ Occurrence:
- •Unicellular eukaryotes
- •Multicellular eukaryotes
- •Haploid, diploid and polyploid cells
- •Somatic cells
- •Reproductive cells
▢ Result: Single cell → 2 daughter cells
▢ Mitocyte: Cell undergoing mitosis
▢ Calculations:
Table 1: Mitosis Formulae
Question Type | Formula |
|---|---|
Total mitotic divisions/events needed to produce n cells from one cell | n − 1 |
Number of cells after n generations | 2ⁿ |
Number of generations to form given cells | 2ⁿ = given number |
▢ Types Based on Spindle Formation:
Table 1: Types of Mitosis
Type | Feature | Common In |
|---|---|---|
Astral / amphiastral mitosis | Mitosis with spindle fibre formation | Animals |
Anastral mitosis | Mitosis without astral spindle formation | Plants |
📚
MITOTIC KARYOKINESIS
▢ Stages:
- •Prophase
- •Metaphase
- •Anaphase
- •Telophase
▢ Important Point: All 4 stages occur continuously without stoppage
📚
PROPHASE OF MITOSIS
▢ Key Features:
- •First stage of mitosis
- •Longest stage of mitosis
- •Metabolically most active stage of cell division
- •Chromatin changes into chromosomes
- •Chromosomes become visible
- •Prophase chromosomes = prochromosomes
- •Spiralisation occurs
- •Spiralisation type = plectonemic coiling
- •Cell becomes more viscous
- •Spindle fibre formation starts during late prophase
- •Nuclear membrane disappears during late prophase
- •Nucleoplasm disappears during late prophase
- •Nucleolus disappears during late prophase
▢ Not Visible:
- •Centromere not visible
- •Chromatids not visible
▢ Spindle Fibre:
- •Made of 97% tubulin protein
- •Made of 3% RNA
▢ CEE Trap:
- •Plectonemic coiling → mitotic prophase
- •Paranemic coiling → meiotic prophase
📚
METAPHASE OF MITOSIS
▢ Key Features:
- •Chromosomes are thickest
- •Chromosomes are shortest
- •Centromere visible
- •Chromatids visible
- •Best stage to study chromosomes
- •Metaphase-II is better than metaphase-I for chromosome study
- •Chromosomes arrange in single line at equator
- •Arrangement at equator = metakinesis
- •Single metaphasic / equatorial plate formed
- •Structure, size and number of chromosomes studied
- •Spindle fibre well developed
- •Spindle fibres from opposite poles attach to kinetochore / primary constriction
- •Idiogram / karyotype prepared
▢ Chromatid Count: Number of chromatids per chromosome = 2 in mitosis and meiosis metaphase
📚
ANAPHASE OF MITOSIS
▢ Synonym: Migratory phase
▢ Key Features:
- •Shortest stage of mitosis
- •Inert / less active stage of cell division
- •Best stage to study chromosome shape
- •Centromere divides
- •Sister chromatids separate
- •Sister chromatids move towards opposite poles
- •Each chromosome has 1 chromatid in anaphase
- •Poleward movement occurs due to spindle fibre and centromere
- •Main force for poleward movement generated by centromere
- •Calcium ions promote anaphase
▢ Chromosome Shapes:
- •V-shaped
- •J-shaped
- •L-shaped
- •I-shaped
▢ Special Note: Chromosome number remains same but chromatid number becomes half compared to metaphase
📚
TELOPHASE OF MITOSIS
▢ Synonym: Re-organisation phase
▢ Key Features:
- •Reverse of prophase
- •Nuclear membrane reappears
- •Nucleolus reappears
- •Chromosomes decondense
- •Chromosomes uncoil
- •Chromosomes reach opposite poles
- •Spindle fibres disappear
- •Chromosomes reorganise
- •Cell resumes metabolic activity
▢ Result: Two daughter nuclei with same chromosome number and same DNA amount
📚
CYTOKINESIS
Table 1: Plant vs Animal Cytokinesis
Feature | Plant Cell | Animal Cell |
|---|---|---|
Method | Cell plate formation | Furrowing / constriction |
Initiating structure | Golgi body initiates cell plate | Microfilaments form contractile ring |
Plane determined by | Microtubules | Microfilaments |
Growth direction | Centrifugal | Centripetal |
Final result | Phragmoplast → cell plate → cell wall | Cleavage furrow divides cytoplasm |
▢ Plant Cell Plate Formation:
- •Spindle fibres aggregate at equator
- •Golgi body initiates cell plate formation
- •Cell plate later converts into phragmoplast and finally cell wall
📚
SPECIAL POINTS OF MITOSIS
▢ Daughter Cells:
- •Same amount of DNA as parent cell
- •Same number of chromosomes as parent cell
- •Genetically identical cells
▢ C-Mitosis:
- •Colchicine-treated mitosis
- •Colchicine = mitotic poison
- •Temporarily stops mitotic division
- •Inhibits spindle fibre formation
- •Breaks microtubules
- •Arrests cell division at metaphase
- •Produces polyploidy
▢ Uncontrolled Mitosis: Leads to neoplasia
▢ Example Calculations:
Table 1: CEE Calculation Examples
Question | Answer |
|---|---|
Mitotic division events needed to form 64 cells | 64 − 1 = 63 total division events |
Generations needed to form 32 cells | 2ⁿ = 32 → n = 5 |
Bacteria divides every 20 min; cells after 2 hr | 2 hr = 120 min; 120/20 = 6 generations; 2⁶ = 64 |
Bacteria fills cup in 60 min, divides every 1 min; half cup time | 59 min |
Bacteria fills cup in 60 min, divides every 3 min; half cup time | 57 min |
📚
SIGNIFICANCE OF MITOSIS
▢ Points:
- •Growth of organism
- •Maintenance of somatic cells
- •Repair of somatic cells
- •Maintains genetic stability
- •Avoids ageing by replacing old cells
- •Produces genetically identical cells resembling zygote
- •Restores surface area : volume ratio
- •Restores nucleocytoplasmic ratio by dividing mature cell into smaller cells
📚
MEIOSIS
▢ Synonyms:
- •Reductional cell division
▢ Introduction:
- •Common in germ cells / reproductive cells
- •Single cell divides to form 4 daughter cells
- •Occurs in pollen mother cell
- •Two divisions of nucleus
- •Only one division of chromosome
- •Meiotic cell = meiocyte
- •Meiocyte divides once in lifetime
- •Meiosis is never followed by meiosis
- •Meiosis can be followed by mitosis
- •In alternation of generation, meiosis is always followed by fusion / fertilization
- •Occurs in diploid and polyploid cells
- •Never occurs in haploid cells
▢ Best Material:
- •Anthers of onion
- •Tradescantia
- •Anther / microsporangium / microspore mother cell
▢ Result Compared to Diploid Parent:
- •Same amount of DNA according to given note
- •Half number of chromosomes
▢ Gamete Production:
Table 1: Spermatocyte / Oocyte Output
Starting Cell | Output |
|---|---|
1 primary spermatocyte / 2n | 4 sperms |
1 primary oocyte / 2n | 1 egg |
1 secondary spermatocyte / n | 2 sperms |
1 secondary oocyte / n | 1 egg |
▢ Double Division:
- •Meiosis-I
- •Meiosis-II
📚
MEIOSIS-I
▢ Nature: Reductional division
▢ Components:
- •Karyokinesis
- •Cytokinesis
▢ Stages:
- •Prophase-I
- •Metaphase-I
- •Anaphase-I
- •Telophase-I
📚
PROPHASE-I
▢ Importance:
- •Longest phase of meiosis
- •Most complex phase of meiosis
- •Longest and most complex phase = Prophase-I
▢ Substages:
Table 1: Prophase-I Substages
Stage | Main Character |
|---|---|
Leptotene | Bouquet formation |
Zygotene | Synapsis |
Pachytene | Crossing over; chiasmata formation starts |
Diplotene | Chiasmata visible / completed; terminalisation starts |
Diakinesis | Terminalisation completes |
📚
LEPTOTENE
▢ Features:
- •Chromosomes are thread-like
- •Chromosomes show beads called chromomeres
- •Bouquet formation occurs
- •Called bouquet stage
- •Best stage for observation of chromomere
▢ Trap:
- •Chromomere = bead structure in meiotic chromosome
- •Nucleosome = bead structure in chromatin
📚
ZYGOTENE
▢ Main Event: Synapsis
▢ Synapsis:
- •Lengthwise pairing of homologous chromosomes
- •Precise chromomere-to-chromomere pairing
- •Also called syndesis / zipping
- •Occurs in zipper-like fashion
- •May begin at centromere, ends or any point
▢ Synaptonemal Complex:
- •Protein complex favouring synapsis
- •Tripartite structure
▢ Bivalent:
- •Each paired homologous chromosome pair = bivalent
- •Exists as dyad / 2-stranded stage in zygotene
- •Bivalent produced in diploid and allopolyploid
- •Multivalent produced in autopolyploid
- •Number of bivalents = half total chromosomes in diploid cell
▢ Other Features:
- •Chromosomes thicken
- •Chromosomes shorten
📚
PACHYTENE
▢ Importance:
- •Longest substage of Prophase-I
- •Most important substage of Prophase-I
- •Chromosomes are thickest
- •Morphological details of chromosome best studied
▢ Crossing Over:
- •Exchange of genetic material / chromatid segment / DNA / genes
- •Occurs at 4-stranded stage
- •Equal exchange between non-sister chromatids of homologous chromosomes
- •Major source of continuous variation in sexually reproducing organisms
- •Ultimate source of variation = mutation
- •Mutation produces discontinuous variation
▢ Crossing Over Frequency: Single crossing over > double crossing over > triple crossing over
▢ Enzymes:
Table 1: Enzymes of Crossing Over
Enzyme | Function |
|---|---|
Endonuclease | Breakdown / nicking |
Unwindase | Separation |
Ligase | Rejoining |
▢ Tetrad Formation:
- •Sister chromatids become visible
- •Bivalent exists as tetrad
- •Tetrad contains 2 homologous chromosomes
- •Tetrad contains 4 chromatids
- •Tetrad contains 2 centromeres
- •Tetrad contains 4 kinetochores
▢ Synapsis Status:
- •Synapsis mature
- •Synaptonemal complex mature
- •Bivalent mature
📚
DIPLOTENE
▢ Features:
- •Chiasmata formation takes place / becomes clearly visible
- •Synaptonemal complex starts dissolving except at chiasmata
- •Chiasmata indicates crossing over
- •Terminalisation starts
▢ Important Clarification:
- •Chiasmata formation starts during pachytene
- •Chiasmata clearly visible during diplotene
▢ Lampbrush Chromosomes:
- •Profuse decondensation occurs
- •Seen in female species producing yolky eggs
- •Examples: all vertebrates and some invertebrates
▢ Human Female: Ovum remains in diplotene stage from birth to puberty; diplotene is longest in human female
📚
DIAKINESIS
▢ Features:
- •Chiasmata disappear due to terminalisation
- •Terminalisation completes
- •Chiasmata move from centromere to telomere in zipper-like fashion
- •At end, each chromosome has two chromatids = dyad
- •Spindle fibre formation starts
- •Nuclear membrane starts disappearing
- •Nucleolus starts disappearing
- •Nucleoplasm starts disappearing
▢ Terminalisation Note:
- •Terminalisation starts before / by diakinesis as per note sequence
- •Terminalisation occurs and ends during diakinesis
📚
SYNAPTONEMAL COMPLEX
▢ Features:
- •Feature of meiotic Prophase-I
- •Characteristic protein mentioned = ubiquitin
- •First observed by Moses
- •Appears in zygotene
- •Persists in pachytene
- •More clear in pachytene
- •Disappears during diplotene
- •Helps proper pairing of homologous chromosomes
- •Helps recombination
📚
METAPHASE-I
▢ Features:
- •Paired homologous chromosomes arrange at equatorial plane
- •Arrangement = congression
- •Chromosomes arrange in two distinct lines
- •Double metaphase plate formed
- •Spindle fibres appear
- •Each chromosome has 2 chromatids and 1 centromere
📚
ANAPHASE-I
▢ Features:
- •Separation of maternal and paternal homologous chromosomes
- •Separation = disjunction
- •Separated chromosomes = univalents / dyads
- •Centromere does not divide
- •Chromosome number reduces to half
- •Chromatid number remains same compared to metaphase-I
📚
TELOPHASE-I
▢ Features:
- •Similar to mitotic telophase
- •Daughter nuclei form after first meiotic division
- •Followed by cytokinesis
📚
INTERKINESIS
▢ Definition: Brief intrameiotic interphase between meiosis-I and meiosis-II
▢ Important Point:
- •No S phase
- •No DNA synthesis
- •Occurs between meiosis-I and meiosis-II
📚
MEIOSIS-II
▢ Synonym: Meiotic mitosis
▢ Nature: Similar to mitosis
▢ Stages:
- •Prophase-II
- •Metaphase-II
- •Anaphase-II
- •Telophase-II
▢ Components:
- •Karyokinesis
- •Cytokinesis
▢ Cytokinesis Types:
Table 1: Cytokinesis in Meiosis
Type | Wall Formation | Tetrad Formed |
|---|---|---|
Successive type | Both meiosis-I and meiosis-II followed by wall formation | Isobilateral tetrads |
Simultaneous type | Meiosis-I not followed by wall formation; wall formation after meiosis-II | Tetrahedral tetrads |
📚
SIGNIFICANCE OF MEIOSIS
▢ Points:
- •Maintains constant chromosome number in sexually reproducing organisms
- •Crossing over causes recombination
- •Recombination has role in evolution
- •Shows basic relationship among organisms
▢ Numerical Points:
- •Number of cytokinesis in meiosis = 3
- •1 cytokinesis in meiosis-I + 2 cytokinesis in meiosis-II
- •Number of spindles in meiosis = 3
- •1 spindle in metaphase-I + 2 spindles in metaphase-II
- •Chromatids per chromosome = 2 in metaphase of mitosis / meiosis
- •Chromatids per chromosome = 1 in anaphase of mitosis
- •Chromatids per chromosome = 2 in anaphase-I of meiosis
📚
MITOSIS VS MEIOSIS
Table 1: High-Yield Comparison
Feature | Mitosis | Meiosis |
|---|---|---|
Common site | Somatic cells | Germ / reproductive cells |
Best material | L.S. onion root tip | Onion / Tradescantia anther |
Number of divisions | One | Two |
Daughter cells | 2 | 4 |
Chromosome number | Maintained | Reduced to half |
Genetic nature | Identical daughter cells | Variable daughter cells due to crossing over |
Synapsis | Absent | Present in zygotene |
Crossing over | Absent | Present in pachytene |
Centromere division | Anaphase | Anaphase-II; not in anaphase-I |
Function | Growth, repair, maintenance | Gamete formation, variation, chromosome number maintenance |
Q1.
Chiasmata formation takes place in [MOE 2058]
📅MOE 2058
Q2.
Meiosis occurs in [MOE 2055]
📅MOE 2055
Q3.
Chromosomes are seen distinctly during [BPKIHS 1997]
📅BPKIHS 1997
Q4.
Mitosis can be clearly observed from: [BPKIHS 1997]
📅BPKIHS 1997
Q5.
The smallest unit of crossing over is [BPKIHS 1998]
📅BPKIHS 1998
Q6.
When only G, phase is operating and others are no operating the phase is [BPKIHS 1998]
📅BPKIHS 1998
Q7.
Synapsin occurs in which stage: [MOE - 2008]
📅MOE - 2008
Q8.
The no. of chromatids in a chromosomes at metaphase is: [MOE-2002]
📅MOE-2002
Q9.
In meiosis cell division, nuclear membrane disappear and chromosomes are separated during: [MOE-2053)
📅MOE-2053)
Q10.
The two daughter cells produced at the end of meiosis when compared to the parent diploid cells will have: [IOM-2004)
📅IOM-2004)
Q11.
Nucleus has maximum size during: [IOM- 20]
📅IOM- 20%
Q12.
Which of the following is associated with division? [IOM-200]
📅IOM-200
Q13.
How many times does a simple cell divide mitotical to form 32 cells? [IOM-20]
📅IOM-20
Q14.
In which stage does centromere divide? [IOM- 20]
📅IOM- 20
Q15.
The inherent capacity of a cell to regenerate a total plant is called. [IOM- 195
📅IOM- 195
Q16.
Interphase, chromatin under electron microscope refers to: [BPKIHS 200]
📅BPKIHS 200
Q17.
The mitosis can be readily observed in: [BPKIHS 200)
📅BPKIHS 200)
Q18.
During meiosis, which is correct? [BPKIHS 2001
📅BPKIHS 2001
Q19.
During which phase chromatids are clearly seen: [BPKIHS 200]
📅BPKIHS 200%
Q20.
Homologous chromosome separate during: [BPKIHS 2002
📅BPKIHS 2002
Q21.
During meiosis gametes produced are: [BPKIHS 2002)
📅BPKIHS 2002)
Q22.
No. of chromosomes in sister cells immediately after mitotic metaphase are: [BPKIHS 2003)
📅BPKIHS 2003)
Q23.
Karyokinesis is the division of:
📅BPKIHS 2005
Q24.
Terminalisation takes place during:
📅BPKIHS 2005
Q25.
The site where meiosis occur in a plant is:
📅BPKIHS 2006
Q26.
A cell stops growing due to storage of nutrients, this would happen in:
📅BPKIHS 2007
Q27.
In cell division replication of DNA occurs in
📅IE - 2002
Q28.
During the start of mitosis the condensed chromosome contains 2
📅IE - 2002
Q29.
Which of the following is the part of mitosis in seed plants?
📅IE - 2002
Q30.
During cell cycle, two molecules of DNA are present in chromosome during
📅IE -2003
Q31.
The transfer of genes from one chromosome to another during synapsis, is termed as:
📅IE - 2004
Q32.
Crossing over occurs during
📅IE - 2005
Q33.
Replication of DNA occurs during
📅IE - 2005
Q34.
The region of attachment of chromosome to spindle fibre is called
📅IE - 2005
Q35.
Segregation of dominant and recessive genes occur during:
📅IE - 2008
Q36.
The point at which crossing over takes place is [BPKIHS - 2016, 2012]
📅BPKIHS - 2016, 2012
Q37.
The phase of cell cycle in which nucleolus and nuclear membrane disappear is [BPKIHS - 2016)
📅BPKIHS - 2016)
Q38.
What is the correct order of prophase I of meiosis I? [BPKIHS - 2013]
📅BPKIHS - 2013
Q39.
Chromosomes becomes distinct and nucleolus as well as nuclear membrane disappears is [BPKIHS - 2012]
📅BPKIHS - 2012
Q40.
Centrosome helps in [BPKIHS - 2011]
📅BPKIHS - 2011
Q41.
Shortest phase of cell cycle is: [BPKIHS - 2010]
📅BPKIHS - 2010
Q42.
Correct sequence of cell cycle is
📅IOM-2014
Q43.
The main significance of M-phase of the cell cycle is
📅IOM-2013
Q44.
Terminalization occurs in
📅IOM-2016
Q45.
The mitotic poison is
📅IOM-2012
Q46.
In which stage chromosome are arranged in equator?
📅IOM-2012
Q47.
In meiosis, bivalent is attached to spindle fiber at
📅IOM-2012
Q48.
The amount of DNA doubles in which mitotic phase
📅MOE 2014
Q49.
At what stage of mitotic division, formation daughter nuclei takes place?[MOE 2016
📅MOE 2016
Q50.
The pairing (synapsid) of chromosome occurs in the following stage of meiosis-I [MOE 2068)
📅MOE 2068)
Q51.
In which stage of the meiotic cell division crossing over occurs? [MOE 2010)
📅MOE 2010)
Q52.
Centromere completely divides into two separate chromatids at [MOE 2010)
📅MOE 2010)